Study: Gene associated with childhood asthma risk

In an article published in an early on-line edition of the journal Nature in July, researchers studied more then 2,000 children and pinpointed a gene called ORMDL3 which is found at higher levels in the blood cells of children with asthma. By comparing the genetic makeup of 994 patients with childhood onset asthma and 1,243 non-asthmatics the researchers were able to determine that markers on chromosome 17 were strongly and reproducibly associated with childhood onset asthma. These markers appeared to alter levels of ORMDL3 and may determine susceptibility to childhood asthma. To view the abstract of the article visit //www.nature.com/nature/journal/vaop/ncurrent/abs/nature06014.html. To view an on-line BBC news article about this study visit //news.bbc.co.uk/2/hi/health/6261876.stm.

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